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J N Mark Glover Selected Research

Proteins (Proteins, Gene)

1/2021Structural insights into DNA double-strand break signaling.
11/2019Domain analysis of PNKP-XRCC1 interactions: Influence of genetic variants of XRCC1.
10/2019Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
1/2017Neurological disorders associated with DNA strand-break processing enzymes.
5/2015Peptide library approach to uncover phosphomimetic inhibitors of the BRCA1 C-terminal domain.
2/2006BRCA1 DNA-binding activity is stimulated by BARD1.
1/2006Insights into the molecular basis of human hereditary breast cancer from studies of the BRCA1 BRCT domain.
11/2004Interactions between BRCT repeats and phosphoproteins: tangled up in two.
6/2004Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1.
12/2003Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations.

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J N Mark Glover Research Topics

Disease

11Neoplasms (Cancer)
01/2021 - 12/2003
4Breast Neoplasms (Breast Cancer)
05/2015 - 12/2003
2Ataxia Telangiectasia (Louis Bar Syndrome)
02/2024 - 07/2011
1Obesity
01/2023
1Hyperglycemia
01/2023
1COVID-19
01/2022
1Neurodevelopmental Disorders
01/2017
1Nervous System Diseases (Neurological Disorders)
01/2017
1Inflammation (Inflammations)
04/2016
1Ovarian Neoplasms (Ovarian Cancer)
06/2010
1Nijmegen Breakage Syndrome
10/2009

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2003
5DNA (Deoxyribonucleic Acid)IBA
11/2019 - 06/2009
2EnzymesIBA
01/2023 - 01/2017
2Peptides (Polypeptides)IBA
05/2015 - 06/2004
1Nalpha- (2- naphthylsulfonyl)- 3- amidinophenylalanine- carboxymethylpiperazideIBA
02/2024
1TransferasesIBA
01/2023
1Coenzyme A (CoA)IBA
01/2023
1Dopamine (Intropin)FDA LinkGeneric
01/2023
1KetonesIBA
01/2023
1Pimozide (Orap)FDA Link
01/2023
1succinyl-coenzyme A (succinyl-CoA)IBA
01/2023
1Antipsychotic Agents (Antipsychotics)IBA
01/2023
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2022
1GlucocorticoidsIBA
01/2022
1Protein Phosphatase 1IBA
10/2019
14-aminophenylphosphate (PNPP)IBA
10/2019
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2017
1UbiquitinIBA
04/2016
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
04/2016
1ChromatinIBA
07/2012
1Phosphotransferases (Kinase)IBA
07/2011
1BRCA1 ProteinIBA
06/2010
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
10/2009
1T-DNAIBA
06/2009
1Peptide Hydrolases (Proteases)FDA Link
12/2003

Therapy/Procedure

2Therapeutics
01/2021 - 01/2017